| Autor: |
Streli, Anna Turyanskaya, Mirjam Rauwolf, Tilman Grünewald, Martin Meischel, Stefanie Stanzl-Tschegg, Jörg Löffler, Peter Wobrauschek, Annelie Weinberg, Helga Lichtenegger, Christina |
| Jazyk: |
angličtina |
| Rok vydání: |
2016 |
| Předmět: |
|
| Zdroj: |
Materials; Volume 9; Issue 10; Pages: 811 |
| ISSN: |
1996-1944 |
| DOI: |
10.3390/ma9100811 |
| Popis: |
This study investigated the distribution of the elemental constituents of Mg-based implants at various stages of the degradation process in surrounding bone tissue, with a focus on magnesium (Mg), as the main component of the alloy, and yttrium (Y), due to its potential adverse health effects. The measurements were performed on the implant-bearing thin sections of rat bone in a time series of implant degradation between one and 18 months. Micro X-ray fluorescence analysis (μXRF) with a special spectrometer meeting the requirements for the measurements of low-Z elements was used. It was found that the migration and accumulation behaviour of implant degradation products is element-specific. A sharp decrease in Mg was observed in the immediate vicinity of the interface and no specific accumulation or aggregation of Mg in the adjacent bone tissue was detected. By contrast, Y was found to migrate further into the bone over time and to remain in the tissue even after the complete degradation of the implant. Although the nature of Y accumulations must still be clarified, its potential health impact should be considered. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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