Synonymous Codon Usage in Bacteria

Autor: Ermolaev, Maria D.
Jazyk: angličtina
Rok vydání: 2001
Předmět:
Zdroj: Current Issues in Molecular Biology
Volume 3
Issue 4
Pages 91-97
ISSN: 1467-3045
DOI: 10.21775/cimb.003.091
Popis: In most bacteria, synonymous codons are not used with equal frequencies. Different factors have been proposed to contribute to codon usage preference, including translational selection, GC composition, strand-specific mutational bias, amino acid conservation, protein hydropathy, transcriptional selection and even RNA stability. The review discusses these factors and their contribution to bias in synonymous codon usage in bacterial genomes.
Databáze: OpenAIRE