Structure and Properties of Composite Fibers Based on Chitosan and Single-Walled Carbon Nanotubes for Peripheral Nerve Regeneration

Autor:	Yudin, Elena N. Dresvyanina, Nurjemal A. Tagandurdyyeva, Vera V. Kodolova-Chukhontseva, Irina P. Dobrovol’skaya, Almaz M. Kamalov, Yulia A. Nashchekina, Alexey V. Nashchekin, Alexey G. Ivanov, Galina Yu. Yukina, Vladimir E.
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	chitosan wet spinning single-wall carbon nanotubes composites peripheral nerve regeneration
Zdroj:	Polymers; Volume 15; Issue 13; Pages: 2860
ISSN:	2073-4360
DOI:	10.3390/polym15132860
Popis:	This study focused on a potential application of electrically conductive, biocompatible, bioresorbable fibers for tubular conduits aimed at the regeneration of peripheral nerves. The conducting, mechanical, and biological properties of composite fibers based on chitosan and single-walled carbon nanotubes were investigated in this paper. It was shown that introducing 0.5 wt.% of SWCNT into the composite fibers facilitated the formation of a denser fiber structure, resulting in improved strength (σ = 260 MPa) and elastic (E = 14 GPa) characteristics. Additionally, the composite fibers were found to be biocompatible and did not cause significant inflammation or deformation during in vivo studies. A thin layer of connective tissue formed around the fiber.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=multidiscipl::54d1369a44d142bd95898110323be981 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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