Autor:	Duchaine, T.F., Slack, F.J.
Jazyk:	angličtina
Rok vydání:	2009
Předmět:	oncomirs sirna Cancer therapy rnai therapy nucleic acid analogs tumour-suppressor mirnas mirna
Zdroj:	Current Oncology Volume 16 Issue 4 Pages 486-66
ISSN:	1718-7729
DOI:	10.3747/co.v16i4.486
Popis:	The discovery that rna interference (rnai) and its functional derivatives, small interfering rnas (sirnas) and micro-rnas (mirnas) could mediate potent and specific gene silencing has raised high hopes for cancer therapeutics. The prevalence of these small (18&ndash 25 nucleotide) non-coding rnas in human gene networks, coupled with their unique specificity, has paved the way for the development of new and promising therapeutic strategies in re-directing or inhibiting small rna phenomena.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=multidiscipl::0ccdbed6b5ef6ef8b171b0f3835eec19 Zobrazit plný text záznamu