Meta-CF3-Substituted Analogues of the GFP Chromophore with Remarkable Solvatochromism

Autor:	Baranov, Maxim Perfilov, Elvira Zaitseva, Nadezhda Baleeva, Vadim Kublitski, Alexander Smirnov, Yulia Bogdanova, Svetlana Krasnova, Ivan Myasnyanko, Alexander Mishin, Mikhail
Jazyk:	angličtina
Rok vydání:	2023
Předmět:	GFP Kaede fluorogen fluorescence endoplasmic reticulum
Zdroj:	International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 9923
ISSN:	1422-0067
DOI:	10.3390/ijms24129923
Popis:	In this work, we have shown that the introduction of a trifluoromethyl group into the me-ta-position of arylidene imidazolones (GFP chromophore core) leads to a dramatic increase in their fluorescence in nonpolar and aprotic media. The presence of a pronounced solvent-dependent gradation of fluorescence intensity makes it possible to use these substances as fluorescent polarity sensors. In particular, we showed that one of the created compounds could be used for selective labeling of the endoplasmic reticulum of living cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=multidiscipl::061267eee8b010c498e235aeb3ede7c2 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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