| Autor: |
Zhao-Hui, Jin, B Tsuji, Atsushi, Mélissa, Degardin, Sugyo, Aya, Obara, Satoshi, Wakizaka, Hidekatsu, Nagatsu, Kotaro, Hu, Kuan, Ming-Rong, Zhang, Dumy, Pascal, Boturyn, Didier, Higashi, Tatsuya, Atsushi, Tsuji, Aya, Sugyo, Satoshi, Obara, Hidekatsu, Wakizaka, Kotaro, Nagatsu, Kuan, Hu, Zhang, Ming-Rong, Tatsuya, Higashi |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Zdroj: |
Clinical Cancer Research. 26(23):6230-6241 |
| ISSN: |
1078-0432 |
| Popis: |
Ovarian cancer peritoneal metastases (OCPMs) are a pathophysiologically heterogeneous group of tumors that are rarely curable. αvβ3 integrin (αvβ3) is overexpressed on tumoral neovessels and frequently on ovarian cancer cells. Here, using two clinically relevant αvβ3-positive OCPM mouse models, we studied the theranostic potential of an αvβ3-specific radiopeptide, 64Cu-cyclam-RAFT-c(-RGDfK-)4 (64Cu-RaftRGD), and its intra- and intertumoral distribution in relation to the tumor microenvironment. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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