Popis: |
Results of research studies for newborn screening were reviewed, which were conducted in the Hokkaido Institute of Public Health for over 25 years. Many technical improvements have been made during this period, assessing the screening results over 30 million newborns in Japan and one million in Hokkaido. Our improvement of analytical techniques, evaluation of each screening result,and pilot studies on additional diseases seem to have contributed to advances in newborn screening program in Hokkaido prefecture. |