Usefulness of Intracardiac Local Ventricular Electrogram to Predict Responders in Patients Undergoing Cardiac Resynchronization Therapy

Autor: ONUMA, Yoshimasa, KAWAMURA, Mitsuharu, YOSHIKAWA, Kosuke, GOKAN, Toshihiko, OGAWA, Ko, NAKAMURA, Yuya, OCHI, Akinori, INOKUCHI, Koichiro, MUNETSUGU, Yumi, ONUKI, Tatsuya, ITO, Hiroyuki, WATANABE, Norikazu, KOBAYASHI, Youichi
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: The Showa University journal of medical sciences. 29(2):131-139
ISSN: 0915-6380
Popis: Cardiac resynchronization therapy (CRT) is a well-established, efficient strategy for medically-refractory congestive heart failure (HF) with ventricular conduction disturbances. However, about 30% of patients who undergo CRT do not receive any benefit. Therefore, we investigated the usefulness of the QRS-left ventricle (LV) interval for predicting responders during CRT implantation. This study included 66 patients who underwent CRT implantation. The definition of responder was a ≥15% reduction in LV end-systolic volume or ≥20% increase in LV ejection fraction. The QRS-LV interval was measured from the beginning of the body surface electrocardiogram QRS complex to the LV potential recorded by LV leads. We analyzed the correlations between the QRS-LV intervals and CRT responders, admission for HF and mortality. The patients were 67±12 years old, and their mean LV ejection fraction was 26.3%±8.3%. During follow-up (27.2±19.9 months), 27 patients were admitted for HF (40.1%), and 17 died (25.7%); the median QRS-LV interval was 103±33 msec. Patients were divided into 2 groups: wide QRS-LV (>103 msec), and narrow QRS-LV (
Databáze: OpenAIRE