One-pot synthesis of 1-arylmethyl-4-[(E)-alk-1-enyl]-1H-1,2,3-triazoles via a cross-coupling/click reaction sequence
| Autor: | Hoshi, Masayuki, Okimoto, Mitsuhiro, Oikawa, Asuka, Miyawaki, Shunsuke, Shimotori, Yasutaka |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Zdroj: | RSC Advances. 4(5):2124-2128 |
| Popis: | 1-Arylmethyl-4-[(E)-alk-1-enyl]-1H-1,2,3-triazoles have been synthesized from terminal conjugated (E)-enynes, prepared by copper-mediated cross-coupling reaction of (E)-alk-1-enyldisiamylboranes with (trimethylsilyl)ethynyl bromide, benzyl bromides and sodium azide in a one-pot fashion. In this cross-coupling/click reaction sequence, the copper precursor Cu(acac)2 can serve as a tandem catalyst. |
| Databáze: | OpenAIRE |
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