Clinical studies on recurrence of acute uncomplicated cystitis
| Autor: | KAMIDONO, Sadao, ARAKAWA, Soichi, KATAOKA, Nobumasa, FUJII, Akio, ISHIGAMI, Joji, HIROOKA, Kyubei, OHBE, Toru, HIKOSAKA, Koji, KATAOKA, Nobuo, SAITO, Hiroshi, KURODA, Yasuji, TAKAHASHI, Yasumasa, OHSHIMA, Hideo, ITO, Noboru, TOMIOKA, Osamu, HINENO, Suguru, TAKADA, Kenji, MITA, Toshihiko, TERASOMA, Kazunori, UEHARAGUCHI, Hiroshi |
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| Jazyk: | japonština |
| Rok vydání: | 1984 |
| Předmět: | |
| Zdroj: | 泌尿器科紀要. 30(4):519-527 |
| ISSN: | 0018-1994 |
| Popis: | 急性単純性膀胱炎の再発につき検討した.(1) CEX単独7日間治療群(C群)と, CEXにLysozyme併用7日間治療群(L群)のうち, 7日目著効が得られた膀胱炎患者を対象に, 14日目の再発を検討した.UTI研究会試案による判定では, 再発率はC群12.2%, L群21.1%で, 両群間に有意差はなかった.(2)7日目からの菌陰性化維持率は, 21日目でC群68.4%, L群85.7%と, リゾチーム併用群で高かった.(3)再発例における菌種, MICの検討から, 再燃と再感染が約1:1でみられた.(4)再発時の所見をみると, 細菌尿, 膿尿が主体であり, 排尿痛は認められないものが多く, かつ患者の主観的症状であることから, 「排尿痛」は再発判定の指標として不適当と考えられ, 細菌尿と膿尿の二項目から判定するUTI研究会試案の妥当性が示唆された Recurrence rate and symptoms after chemotherapy against acute uncomplicated cystitis (AUC) were studied. Upon completion of a 7-day treatment with two regimens, one of CEX alone (Group C) and the other of a combination of CEX with Lysozyme (Neuzym) (Group L), at a dose of 1 g CEX daily, efficacy of the drugs was assessed according to the criteria established by the UTI Study Group. The forty one cases in Group C and 38 cases in Group L showing an excellent response were evaluated for recurrence. The rates of recurrence were 12.2% in Group C and 21.1% in Group L during the first 7 days after treatment. In recurrent cases, bacteriuria was seen in 84.6% (11/13), pyuria in 53.8% (7/13) and miction pain in 30.8% (4/13). Thus, bacteriuria and pyuria should be the items of the criteria for AUC recurrence. |
| Databáze: | OpenAIRE |
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