Active Immunization Against 5α-androstane-3α, 17β-diol Increases Ovulation Rate in Merino Ewes

Autor:	Tetsuka, Masafumi, Nancarrow, Colin. D.
Jazyk:	angličtina
Rok vydání:	2001
Předmět:	endocrine system Sheep Ovulation rate Immunization 5a-reduced androgen hormones hormone substitutes and hormone antagonists
Zdroj:	Journal of Reproduction and Development. 47(1):7-15
ISSN:	0916-8818
Popis:	application/pdf Cyclic Merino ewes were immunized three times against 5α−androstane-3α,17β-diol (3α-diol) at three week intervals (weeks 0,3 and 6). After the third immunization, estrous cycles were synchronized by a series of PG injections and intensive blood samples were obtained for gonadotropin analyses during the mid-luteal phase and during the early follicular phase. Ovulation rates were determined after each immunization and subsequent cloprostenol (PG)-induced luteolysis (weeks 3, 6, 8 and 11). After the second immunization, daily blood samples were obtained and concentrations of plasma progesterone (P) were measured. Immunization against 3α-diol significantly increased the ovulation rate after the second and third immunizations and at week 10 (P
Databáze:	OpenAIRE
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