| Autor: |
Kawashiri, Shin-ya, Kawakami, Atsushi, Fujikawa, Keita, Iwamoto, Naoki, Aramaki, Toshiyuki, Tamai, Mami, Nakamura, Hideki, Origuchi, Tomoki, Ida, Hiroaki, Eguchi, Katsumi |
| Jazyk: |
angličtina |
| Rok vydání: |
2010 |
| Předmět: |
|
| Zdroj: |
Internal Medicine. 49(5):487-490 |
| ISSN: |
0918-2918 |
| Popis: |
Type B insulin resistance is characterized by the appearance of autoantibodies to the insulin receptor. We present a 59-year-old Japanese man with type B insulin resistance complicated with systemic lupus erythematosus (SLE). A high titer of anti-insulin receptor autoantibodies was revealed when SLE was defined as active disease. Intravenous boluses of cyclophosphamide (IVCY) with oral prednisolone and cyclosporin A induced remission of SLE, and a subsequent disappearance of anti-insulin receptor autoantibodies, followed by a recovery of glucose intolerance. This is a rare and important case report showing a clear correlation between anti-insulin receptor autoantibodies of type B insulin resistance and SLE disease activity. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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