COMBINATION CHEMOTHERAPY WITH CIS-DIAMMINEDICHLOROPLATINUM, BLEOMYCIN AND VINCRISTINE FOR STAGE 4 RENAL ADENOCARCINOMA

Autor: Fujii, Akio, Arakawa, Soichi, Hazama, Minoru, Nakano, Yasuharu, Yamanaka, Nozomu, Hamami, Gaku, Umezu, Keiichi, Sugimoto, Masayuki, Kamidono, Sadao, Ito, Noboru, Hikosaka, Koji
Jazyk: japonština
Rok vydání: 1982
Předmět:
Zdroj: 泌尿器科紀要. 28(6):741-746
ISSN: 0018-1994
Popis: Combination intensive therapy of cis-diamminedichloroplatinum (CDDP), bleomycin (BLM) and vincristine (VCR) was administered to 5 patients with stage IV renal adenocarcinoma, all of whom had received nephrectomy. Following this 2-3-month intensive therapy, maintenance therapies consisting of CDDP.BLM.VCR and CDDP.VCR were given. Two patients achieved objective responses (I patient: complete remission), and 1 patient achieved a subjective response. One patient died of side effects. Renal dysfunction with elevation of serum creatinine was seen in 2 patients, a leucocyte count of less than 1000/mm3 in I patient, and pulmonary fibrosis in 2 patients.
Databáze: OpenAIRE