TSAA-291(16β-Ethyl-17β-Hydroxy-4-Oestren-3-One)の中枢への影響

Autor: Shimazaki, Jun, Miyauchi, Taisei
Jazyk: japonština
Rok vydání: 1982
Předmět:
Zdroj: 泌尿器科紀要. 28(4):387-390
ISSN: 0018-1994
Popis: Plasma hormone levels were determined before and after administration of TSAA-291 for 12 weeks and 1-2 months after final administration. The following results were obtained. 1) Gonadotropin levels showed a tendency to decline after administration and did not recover 1-2 months after final administration. The response of gonadotropins to LH-RH was more clearly suppressed. 2) Testosterone and 5a-dihydrotestosterone levels slightly decreased after drug administration and did not recover 1-2 months after final administration. 3) Cortisol level was not affected by TSAA-291. These results suggest that TSAA-291 has a slight suppressive effect on the hypothalamo-pituitary axis.
Databáze: OpenAIRE