Popis: |
In the winter of 1980, a nutritional disease accompainied by mass mortality occurred in rainbow trout (Salmo gairdneri) at a fish-farm in Tochigi Prefecture. Diseased fish had a thin,black-colored body and pale liver and gill. Histopathological symptoms were represented by myopathy of the systemic skeletal musculature and a extensive deposition of lipopigment in viscera. In the skeletal musculature, most of muscle fibersexhibited mild atrophy and some of the fibers underwent vaious alterations ; central nucleation, extreme atrophy and necrosis within the atrophic fibers, Lipopigment was made up of ceroid and lipoprotein. The lipopigment deposition was extensive within hepatocytes, cardiac muscle, smooth muscle of digestive tubes and macyophages present in the spleen, the hematopoietic tissue, gills and the skin. Hemosiderosis occurred also within the spleen. Based on results from the histopathological research, it was judged that this disease, represented by myopathy and ceroidosis was due to feeding on a rancid diet. |