Autor: |
Fukuoka, Seiji, Seo, Yoshinobu, Takanashi, Masami, Nakagawara, Jyoji, Takahashi, Shuhei, Sasaki, Takehiko, Nakamura, Jun-Ichi, Suematsu, Katsumi |
Jazyk: |
angličtina |
Rok vydání: |
1994 |
Předmět: |
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Zdroj: |
北海道脳神経疾患研究所医誌 = Journal of Hokkaido Brain Research Foundation. 7(1):12-18 |
ISSN: |
1340-5764 |
Popis: |
One hundred and sixty lesions in 68 patients with brain metastases were treated with gamma knife. Thirty four patients had multiple metastases. The mean follow-up was 8.3 months ( 1 to 25 months). More than 50 % reduction rate of tumors were observed 88% of all lesions in one month, 90% in final follow-up. Mean Karnofsky performance status score raised in values from 75% to 89% in one month after gamma knife surgery. Progressive neurological symptoms improved in 89 % of patients with symptoms within one week. Recurrences occurred in 4 %, and transient neurological deteriorations were observed in 7 % of all patients. No permanent deficits was recognized. The median survival was 10 months of all patients ,while 9 months in single lesion and 13 months in multiple lesions respectively. There was no significant difference between these two groups (p=0.96). These data may indicate that gamma knife surgery has rapid effect for brain metastases and is effective for even multiple brain metastases. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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