| Autor: |
Takeda, Masayuki, Katayama, Yasushi, Tsutsui, Toshiki, Sato, Shotaro |
| Jazyk: |
angličtina |
| Rok vydání: |
1992 |
| Zdroj: |
Acta medica et biologica. 40:1-9 |
| ISSN: |
0567-7734 |
| Popis: |
The value of various imaging techniques and urinary parameters for the assessment of reflux nephropathy was examined in 183 patients with primary vesicoureteric reflux attending Niigata University Hospital. 1. To detect scarring, dimercaptosuccinic acid (DMSA) planar renal scintigraphy was superior to intravenous pyelography, while both DMSA SPECT scintigraphy and magnetic resonance imaging were superior to DMSA planar scintigraphy. 2. ^Tc-DMSA uptake was measured in patients with reflux as an index of absolute split renal function. Although the DMSA- uptake of kideney with reflux up to grade 3 was within normal limits in children, many adults with lower grades of reflux showed decreased DMSA uptake. 3. Both the urinary β2-microglobulin index and N-acetyl β-D-glucosaminidase (NAG) index increased with the grade of reflux. However, many patients with low-grade reflux showed a high NAG index despite a normal β2-microglobulin index. Neither of these indices determined at the first visit could predict the change of serum creatinine after treatment. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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