| Autor: |
AKAMA, Tomonori, NOGUCHI, Natsuko, NAGATO, Hajime, UMEBAYASHI, Yoshihiro, ITAMI, Satoshi, OMOKAWA, Susumu, TABATA, Yasuhiko, MANABE, Motomu |
| Jazyk: |
angličtina |
| Rok vydání: |
2009 |
| Předmět: |
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| Zdroj: |
秋田医学. 35(3/4):239-245 |
| ISSN: |
0386-6106 |
| Popis: |
Platelet-derived factors messenger to regulate a well-orchestrated and complex series of events involving cell-cell and cell-matrix interactions and play a key role during the various phases of the wound-repair process. To evaluate the effects of controlled release of platelet-derived factors, we performed the subcutaneous implantation of gelatin hydrogel loaded with frozen-pooled platelet-rich plasma into the back of mice. Consequently, a successful enhancement of collagen formation was observed at the subcutaneous tissues on day 14. The present study reveals that this novel therapeutic approach is hopeful to improve the recovery of healing-impaired cutaneous wound. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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