| Autor: |
Naoto, Kuroda, Saki, Akazawa, Takushi, Naroda, Masato, Tamura, Kenji, Yorita, Yosuke, Fukiishi, Hideo, Fukuhara, Takashi, Karashima, Keiji, Inoue |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
高知赤十字病院医学雑誌 = Medical Journal of Kochi Red Cross Hospital. 23(1):7-12 |
| ISSN: |
0919-7427 |
| Popis: |
The prognosis of chromophobe renal cell carcinoma (RCC) is generally favorable. However, someinvestigations argue against this point of view. In this article, we performed clinicopathologic study ofeight cases of chromophobe RCC with focus on prognostic factors. The incidence of chromophobe RCCaccounts for 7.3% of total renal tumors. In six patients, tumor was incidentally discovered. Aggressiveform was observed in three patients who died of disease in one or showed the distant metastasis in two.Four tumors macroscopically showed more than 8 cm in maximum diameter, which all showed necrosis.Among these tumors, three tumors showed pathologically more than stage III, more than CTG 2, andvascular invasion. Two among these three tumors contained unusual morphological finding, namelyneuroendocrine differentiation or breast cancer-like morphology. Five tumors showed CTG 1 and StageI, which showed neither recurrence nor metastasis. Finally, several factors such as more than 8cm inmaximum diameter, macroscopic necrosis, vascular invasion, more than CTG 2 and usual histologicfeatures including neuroendocrine differentiation and mammary-like carcinoma may be worse prognosticindicators in chromophobe RCC. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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