Susceptibility of different mouse strains to experimental infection with a Venezuelan isolate of Trypanosoma evansi

Autor:	Perrone, Carmona Trina Mercedes, Garrizzo, Juan, Roschman-González, Antonio, Tejero, Felix, Escalante, Ananías, Aso, Pedro María
Jazyk:	angličtina
Rok vydání:	2006
Předmět:	Trypanosoma evansi experimental infection mouse susceptibility
Zdroj:	The journal of protozoology research. 16(1-2):1-8
ISSN:	0917-4427
Popis:	application/pdf The susceptibility of BALB/c, C57Bl/6, DBA/2, NMRI, NIH and CD1 mouse strains to experimental infection with a Venezuelan equine isolate of Trypanosoma evansi was examined through hemoglobin concentration, packed red cell volume, number of erythrocytes per blood μl, parasitemia, body weight, and mice survival time. The said variables seem to be suitable markers to contrast the mouse susceptibility to T. evansi experimental infections. Among the evaluated mouse strains, NMRI was the more susceptible and DBA/2 the less vulnerable to the local T. evansi isolate used in the study. The resistant mouse strains could help in the identification of factors conferring natural resistance against T. evansi, while the susceptible could be used to investigate the heterogeneity of virulence observed in this parasite.
Databáze:	OpenAIRE
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