A COMBINATION THERAPY OF HYPERTHERMIA AND BLEOMYCIN FOR BLADDER CANCER

Autor: Nakajima, Kazuyoshi, Hisazumi, Haruo, Uchibayahsi, Tadao, Naito, Katsusuke, Misaki, Toshimitsu, Kuroda, Kyoichi, Miyazaki, Kimiomi, Fujita, Yukio, Taya, Tadashi, Kameda, Kenichi
Jazyk: japonština
Rok vydání: 1980
Předmět:
Zdroj: 泌尿器科紀要. 26(9):1153-1161
ISSN: 0018-1994
Popis: Physiological saline solution containing 30 to 90 µg/ml of bleomycin was used as a perfusate in 13 patients; 7 with superficial bladder cancer and 6 with deep bladder cancer, at 43°C for 1 to 3 hours. Prior to treatment, the nature and extent of the tumor was determined by cystoscopy, intravenous urography, bimanual palpation under anesthesia, and biopsy specimens of the tumor. The therapeutic effect of the hyperthermic perfusion was evaluated by the same manner. Partial tumor regression was obtained in 5 patients; 2 patients with superficial tumors and 3 with deep tumors. Two patients with intractable gross hematuria were controlled successfully. Most of the patients had bladder discomfort during or after perfusion, and 3 patients developed acute pyelonephritis.
Databáze: OpenAIRE