Metastatic rectal carcinoma from endometrial adenocarcinoma : a case report and review of the Japanese cases

Autor: Teruya, Tsuyoshi, Nakachi, Atsushi, Doi, Shoko, Maehama, Toshiyuki, Kiyuna, Masaya, Department of Surgery, Tomishiro Central Hospital, Department of Obstetrics and Gynecology, Tomishiro Central Hospital, Department of Pathology, Tomishiro Central Hospital
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: 琉球医学会誌 = Ryukyu Medical Journal. 36(1-2):29-36
ISSN: 1346-888X
Popis: We report a rare case of metastatic rectal carcinoma from endometrial adenocarcinoma , and review the Japanese cases. A 61-year-old woman underwent total abdominal hysterectomy and bilateral salpingo-oophorectomy and pelvic lymphadenectomy for endometrial adenocarcinoma and metastatic ovarian tumors. Four years later, a follow-up examination using positron emission tomography-computed tomography revealed a rectal tumor with high 18F-fluorodeoxyglucose accumulation. Colonoscopy subsequently revealed a submucosal tumor on the rectum, and the biopsy specimen revealed adenocarcinoma. As the distant metastasis was not recognized at the other examinations, we performed surgical resection of the rectal tumor. Pathological examination of the resected specimen revealed that the tumor was endometrioid adenocarcinoma with squamous differentiation with positive immunohistochemical staining for cytokeratin 7 and negative staining for cytokeratin 20 and CD10, positive for estrogen receptor and progesterone receptor. These findings suggest that the rectal tumor was metastasis from the endometrial adenocarcinoma. We should follow-up for gynecological lesions with that possibility in mind, and the resection of metastatic colorectal carcinoma can help to improve the prognosis which should be considered in similar cases.
Databáze: OpenAIRE