Time-course of deltaR2 during visual stimulation and hypercapnia diffusion-weighted fMRI experiments

Autor: Kuroiwa, Daigo, Kawaguchi, Hiroshi, Kershaw, Jeffrey, Tachibana, Atsumichi, Joonas, Autio, Hirano, Masaya, Aoki, Ichio, Kanno, Iwao, Obata, Takayuki
Jazyk: angličtina
Rok vydání: 2010
Popis: It has been suggested that the BOLD effect contributes to heavily diffusion-weighted (DW) fMRI signal changes. The BOLD effect is usually interpreted as a change in transverse relaxation rate (deltaR2). In this study, deltaR2 during visual stimulation (VS) and hypercapnia (HC) DW fMRI experiments was estimated using a multiple spin-echo EPI acquisitions after motion-probing gradients. deltaR2 showed dependence on b-value during VS, but not during HC. The results suggest that deltaR2 at high b-value may demonstrate a higher sensitivity to neuronal activation than at lower b-values.
18th Scientific Meeting & Exhibition
Databáze: OpenAIRE