| Autor: |
Yasuda, Takashi, Hokama, Akira, Takaesu, Hiroshi, Shimabuku, Masamori, Tomori, Takehiko, Kiyuna, Masaya, Division of Surgery, Hokubuchiku Ishikai Hospital, Nago City, Okinawa Japan |
| Jazyk: |
angličtina |
| Rok vydání: |
2001 |
| Předmět: |
|
| Zdroj: |
琉球医学会誌 = Ryukyu Medical Journal. 20(1):31-34 |
| ISSN: |
1346-888X |
| Popis: |
Endocrine cell carcinoma (small cell carcinoma) of the gallbladder with elevated serum levels of carcinoembryonic antigen (CEA) in a 78-year-old Japanese woman is herein reported. The patient presented with a painless large mass in the right upper quadrant. Admission laboratory findings showed only an abnormal serum level of CEA. An abdominal ultrasonography (US) showed an echogenic large mass measuring 6 cm in diameter and several small gallstones. An abdominal computed tomography (CT) scan demonstrated a large hyperdensity mass occupying the body and neck of the gallbladder. At laparotomy, the gallbladder tumor showed hepatic infiltration and regional lymph node metastasis. Radical surgery for gallbladder carcinoma was thus performed. The gallbladder tumor was diagnosed to be Stage III. A large, sessile polypoid tumor measuring 6 cm in greatest dimension in the body and neck was found. The tumor was composed of intermediate cells which were histochemically and immunohistochemically positive for chromogranin A, neuron-specific enolase (NSE) and CEA. After being discharged, anticancer agents (Mitomycin C or cisplatin and 5-fluorouracil) was administered on an outpatient basis (small dose) for 2 years while taking great care to reduce any potential side effects. Finally, the patient died due to a recurrence of gallbladder carcinoma 27 months after surgery. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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