Isolation and identification of human skin fibroblast cell growth factor (SFGF) from the scallop shells
| Autor: | TORITA, Akane, YOSETANI, Naomi, HASEGAWA, Yasushi |
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| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: | |
| Zdroj: | 室蘭工業大学紀要 = Memoirs of the Muroran Institute of Technology. 59:95-99 |
| ISSN: | 1344-2708 |
| Popis: | We have previously shown that scallop shells contain bioactive components. In particular, the scallop shell extract promoted the growth of human skin fibroblast cells and increased in the synthesis of collagen in the fibroblast cells. However, the bioactive substance in the scallop shell remains has been unidentified. In this study, we performed the isolation and identification of human skin fibroblast cell growth factor (SFGF) from scallop shell. The SFGF was purified by a gel filtration column (G-2000SW) and subsequently reverse-phase column chromatographies (C4 and C18). The isolated SFGF was presumed to be a glycopeptide with a molecular weight below 3000 Da. This is the first report about the isolation of a bioactive substance from scallop shell. 特集 : 「資源、新エネルギー、環境、防災研究国際セミナー」 |
| Databáze: | OpenAIRE |
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