| Autor: |
Naito, Katsusuke, Hisazumi, Haruo, Saka, Akira, Nakamura, Takeo, Kanda, Shizuto, Mikawa, Ikuo, Ejiri, Susumu, Miyagi, Tetsusaburou, Katsumi, Tetsurou, Kitagawa, Kiyotaka, Okumura, Ryouji, Kawaguchi, Kouhei, Orito, Matsuo, Kameda, Kenichi, Shoda, Ryouchyu, Shimada, Kouichirou, Nakajima, Shinichi, Nango, Chiaki, Miyazaki, Kimiomi, Kosaka, Satoshi, Hashimoto, Kazuo |
| Jazyk: |
japonština |
| Rok vydání: |
1990 |
| Předmět: |
|
| Zdroj: |
泌尿器科紀要. 36(4):487-494 |
| ISSN: |
0018-1994 |
| Popis: |
To evaluate the effect of UFT, a mixture of ftorafur and uracil in a ratio of 1:4, in preventing postoperative recurrence of bladder cancer, we performed a randomized controlled study with a non-medication group as control. UFT was given orally 400 mg a day for 6 months. Of 111 patients, 56 were given UFT and 55 were followed up without any medication. The non-recurrence rate in the group treated with UFT was 62.8% after 1 year and 36.3% after 2 years of follow up, and that of the control group was 45.7% and 39.5%, respectively. The rate of non-recurrence in the UFT group was significantly higher (p less than 0.05) than that of the control group during the period of follow up for 2 years. The incidence of side effects was 6.8% in UFT patients. These results indicate the clinical usefulness of prophylactic administration of UFT for bladder cancer patients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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