Dose‐dependent associations between prenatal caffeine consumption and small for gestational age, preterm birth, and reduced birthweight in the Japan Environment and Children's Study

Autor: Kobayashi, Sumitaka, Sata, Fumihiro, Murata, Katsuyuki, Saijo, Yasuaki, Araki, Atsuko, Miyashita, Chihiro, Itoh, Sachiko, Minatoya, Machiko, Yamazaki, Keiko, Ait Bamai, Yu, Kishi, Reiko, Kawamoto, Toshihiro, Saito, Hirohisa, Yaegashi, Nobuo, Hashimoto, Koichi, Mori, Chisato, Itoh, Shuichi, Yamagata, Zentaro, Inadera, Hidekuni, Kamijima, Michihiro, Nakayama, Takeo, Iso, Hiroyasu, Shima, Masayuki, Hirooka, Yasuaki, Suganuma, Narufumi, Kusuhara, Koichi, Katoh, Takahiko
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Zdroj: Paediatric and Perinatal Epidemiology. 33(3):185-194
ISSN: 0269-5022
Popis: Background: Few previous studies have investigated the association between prenatal caffeine intake and birth size (small-for-gestational-age (SGA), preterm birth, and birthweight Z-score) in Japan. Objectives: We examined the dose-dependency of this association (prenatal caffeine consumption and birth size) as part of the Japan Environment and Children’s Study. Methods: A prospective birth cohort included 94,876 fetuses in Japan. Participants were enrolled between January 2011 and March 2014. Adjusted multiple linear regression and Cox regression models were used to examine the association between prenatal caffeine levels and infant birth size. Results: The median estimated caffeine consumption during pregnancy was 125.5 mg/day, as determined by self-administered questionnaires. There were 7,252 SGA infants (7.6%) and 4,281 preterm birth infants (4.5%). Compared with infants of mothers whose caffeine consumption during pregnancy was in the lowest quartile (4.2 to
Databáze: OpenAIRE