| Autor: |
Okahisa, Toshiya, Sogabe, Masahiro, Hayashi, Shigehito, Shibata, Hiroshi, Ito, Susumu |
| Jazyk: |
angličtina |
| Rok vydání: |
1998 |
| Předmět: |
|
| Zdroj: |
The Journal of Medical Investigation. 45(1-4):87-93 |
| ISSN: |
1343-1420 |
| Popis: |
The contrast medium-removing effect of hemofiltration (HF) and hemodiafiltration (HDF) was experimentally investigated using a bovine blood tank model. HF and HDF were performed at a blood flow rate of 100ml/min with a polysulfone hemofilter (PS filter-CF ; membrane area : 0.7 m2). Two hundred milliliters of iomeprol (300 mgI/ml) was administered by a single injection into 4 liters of bovine blood. The blood half-lives of iomeprol were 1.0 hr for the high flow rate HDF group [replacement fluid flow rate (QF) : 10 ml/min and dialysate flow rate (QD) : 40 ml/min], 1.8 hr for the HDF group (QF : 10 ml/min and QD : 10 ml/min), and 3.8 hr for the HF group (QF : 10 ml/min). The mean clearance rates were 39.7 ml/min for the high flow rate HDF group, 21.4 ml/min for the HDF group, and 12.0 ml/min for the HF group. Iomeprol was mostly excreted in the waste fluid. It is concluded that HDF can remove contrast media more effectively than HF. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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