Autor: |
Hashimoto, Miki, Itonaga, Hidehiro, Nannya, Yasuhito, Taniguchi, Hirokazu, Fukuda, Yuichi, Furumoto, Takafumi, Fujioka, Machiko, Kasai, Sachie, Taguchi, Masataka, Taniguchi, Hiroaki, Sato, Shinya, Sawayama, Yasushi, Atogami, Sunao, Iwasaki, Keisuke, Hata, Tomoko, Soda, Hiroshi, Moriuchi, Yukiyoshi, Nakata, Koh, Ogawa, Seishi, Miyazaki, Yasushi |
Jazyk: |
angličtina |
Rok vydání: |
2020 |
Předmět: |
|
Zdroj: |
Internal Medicine. 59(8):1081-1086 |
ISSN: |
0918-2918 |
Popis: |
Secondary pulmonary alveolar proteinosis (sPAP) is a complication of myelodysplastic syndrome (MDS). A 60-year-old woman was diagnosed with MDS with excess blasts-1. Fifty-four months after the initial diagnosis, treatment with azacitidine was initiated. Seventy-three months after the diagnosis, a bone marrow examination revealed increased myeloblasts, at which time computed tomography showed diffuse ground-glass opacities and interlobular septal thickening in the bilateral lower lung fields. A lung biopsy revealed the presence of PAP; therefore, the clinical diagnosis of MDS/sPAP was confirmed. Careful attention should be paid to the development of sPAP in MDS patients with pulmonary lesions during azacitidine treatment. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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