Nano-honeycomb electrode based QCM sensor and its application for PPI detection

Autor:	Asai, Naoto, Matsumoto, Naohiro, Kazama, Nozomi, Nagaoka, Yasuo, Sumiyoshi, Takaaki, Shimizu, Tomohiro, Shingubara, Shoso, Ito, Takeshi
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	protein-protein interaction 関西大学研究拠点形成支援経費 関西大学 quartz crystal microbalance (QCM) technology industry and agriculture real time detecting Kansai University Biosensor
Zdroj:	IEEE Sensors Journal.
ISSN:	1530-437X
Popis:	An anodic aluminon oxide (AAO)-based nano honeycomb electrode was coated on a quartz crystal for use as a sensing device in a quartz crystal microbalance (QCM) to monitor the protein-protein interactions (PPIs). As examples, we detected PPIs of anti-Bcl-2 and Bcl-2, and Bcl-2 and Bax in real time. A sensor with a flat Au electrode showed a tiny frequency shift upon sample injection. However, our fabricated device could detect 10 μg/mL of Bcl-2 and Bax in sequence. 2016年度関西大学研究拠点形成支援経費
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=jairo_______::225822432981ec1440a055155ea49504 https://kansai-u.repo.nii.ac.jp/records/680 Zobrazit plný text záznamu