Autor: |
Sogawa, Yuka, Fukui, Makoto, Nakamura, Shingen, Sogabe, Kimiko, Sumitani, Ryohei, Yoshioka, Masami, Abe, Masahiro, Hinode, Daisuke |
Jazyk: |
angličtina |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
International Journal of Hematology. 112(6):851-859 |
ISSN: |
0925-5710 |
Popis: |
The aim of this study is to investigate the association between chemotherapy-induced fever with neutropenia less than 1,500/μL (FwN) and oral bacteria and/or oral immunity in patients with hematological cancer. Thirty-two patients with hematological cancer were enrolled in the study. Secretory immunoglobulin A (sIgA) in saliva and the anaerobic bacteria in tongue coating of each subject was assessed before the first chemotherapy. Eleven subjects had an onset of FwN and 21 subjects did not during the observation periods. It was revealed by the cox-proportional hazard model analysis that the levels of sIgA were low (HR 0.98, p |
Databáze: |
OpenAIRE |
Externí odkaz: |
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