| Autor: |
SUGIURA, KENICHI, HASHIZUME, YOSHIO, KUME, AKITO, TAKAHASHI, AKIRA |
| Jazyk: |
angličtina |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
Nagoya Journal of Medical Science. 58(3-4):117-126 |
| ISSN: |
0027-7622 |
| Popis: |
Neuronal cytoplasmic inclusions (NCls) were demonstrated by means of silver staining (Gallyas staining) in the central nervous systems of 18 deceased patients with multiple system atrophy (MSA) - 6 with olivopontocerebellar atrophy (OPCA), 6 with striatonigral degeneration (SND) and 6 with Shy-Drager syndrome (SDS). We observed NCls in the cerebral cortex, putamen, pons, medulla oblongata and spinal cord, and especially in the putamen and pons of all cases with MSA. No NCls were observed in the cerebellum and midbrain. The findings were common to all 3 subtypes of MSA. NCls were not present in patients with other neurodegenerative disorders and non-neurological disorders. Our findings indicate that NCls represent a special neuronal alteration characteristic of MSA and support the theory that OPCA, SND and SDS represent manifestations of a single condition i.e. MSA. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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