重力環境の変化とラット海馬および扁桃体におけるシナプス可塑性
| Autor: | Zeredo, Jorge, Kumei, Yasuhiro, Shimokawa, Reiko, Oya, Keiichi, Shimokawa, Hitoyata, Kimoto, Mari, Okada, Yukio, Toda, Kazuo |
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| Jazyk: | japonština |
| Rok vydání: | 2005 |
| Předmět: | |
| Zdroj: | 宇宙利用シンポジウム 第21回 平成16年度 = Space Utilization Research: Proceedings of the Twenty-first Space Utilization Symposium. :225-227 |
| Popis: | The effects of 2 G hypergravity on the synaptic plasticity of hippocampus and amygdale were examined. After 5 min exposure to 2 G, rats were sacrificed and brain slices were prepared immediately. LTP (Long Term Potentiation) was analyzed by measuring the change in the amplitude of the negative deflection of field potential in hippocampus CA1 (Cornu Ammonis 1) and basolateral amygdala nucleus after tetanus stimulus of the Schaffer Collateral or entorhinal cortex, respectively. It was found that hypergravity significantly increased the efficiency of synaptic transmission in both hippocampus and amygdala. The synaptic plasticity in the limbic system might be a primarily sensitive response site to gravity change. 資料番号: AA0048095051 |
| Databáze: | OpenAIRE |
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