Autor: |
Imaizumi, Akiko, Obata, Takayuki, Kershaw, Jeff, Tachibana, Yasuhiko, Inubushi, Masayuki, Koizumi, Mitsuru, Yoshikawa, Kyosan, Ming-Rong, Zhang, Tanimoto, Katsuyuki, Harada, Rintaro, Uno, Takashi, Saga, Tsuneo, Kershaw, Jeffrey |
Jazyk: |
angličtina |
Rok vydání: |
2019 |
Předmět: |
|
Zdroj: |
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine. 19(3):276-281 |
ISSN: |
1347-3182 |
Popis: |
We investigated the usefulness of diffusion-weighted imaging (DWI) for detecting changes in the structure of hypoxic cells by evaluating the correlation between F-fluoroazomycin arabinoside (FAZA) positron emission tomography activity and DWI parameters in head and neck carcinoma. The diffusion coefficient corresponding to the slow compartment of a two-compartment model had a significant positive correlation with FAZA activity (ρ = 0.58, P = 0.016), whereas the diffusional kurtosis from diffusion kurtosis imaging had a significant negative correlation (ρ = -0.62, P = 0.008), which suggests that those DWI parameters might be useful as indicators for changes in cell structure. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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