Clinical Utility of Prenatal Head-to-Abdominal Circumference Ratio for Prediction of Small-for-Gestational-Age Birth: A Retrospective Study
| Autor: | Takako, Toyama, Kotaro, Hine, Kenichi, Maruyama, Yurika, Ishida, Sachiko, Hirota, Hitoshi, Yoda |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Toho Journal of Medicine. 3(1):17-25 |
| ISSN: | 2189-1990 |
| Popis: | Original Article Background: Head-to-abdominal circumference (HC/AC) ratio on prenatal ultrasonography is useful for diagnosis of intrauterine growth retardation. This study assessed the utility of an HC/AC ratio cut-off point for predicting small-for-gestational-age (SGA) birth. Methods: We retrospectively studied perinatal data from 177 neonates: 36 were classified as being SGA with systemic disease, 23 as SGA without systemic disease, 78 as appropriate-for-gestational-age (AGA) with systemic disease, and 40 as normal. Results: HC/AC ratio correlated with gestational age (r = -0.322, p = 0.024) in the normal group but not in the other groups (SGA with disease group, r = -0.116, p = 0.316; SGA without disease, r = -0.350, p = 0.085; AGA with disease, r = -0.121, p = 0.123). An HC/AC ratio cut-off value of 1.15 identified risk of SGA at birth (sensitivity, 70%; specificity, 65%; p < 0.0001). An HC/AC ratio greater than 1.15 on follow-up ultrasonography was associated with increased risk of SGA at birth (odds ratio, 8.727; 95% confidence interval, 2.987 - 25.498; p < 0.001). Conclusions: Prenatal HC/AC ratio did not decrease in SGA neonates. HC/AC ratio predicted the incidence of SGA at birth, regardless of gestational age. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|