[原著]Changes of fibrinolytic activityin the circulating blood of patients after open heart surgery

Autor: Kosugi, Tadayoshi, Nakamura, Mariko, Okuda, Yoshiaki
Jazyk: angličtina
Rok vydání: 1986
Předmět:
Zdroj: 琉球大学医学会雑誌 : 医学部紀要 = Ryukyu medical journal. 9(3-4):160-167
ISSN: 0289-1530
Popis: Following surgical operations, it has beeri reported that the fibrinolytic activity may be increased in the circulating bloold. In this study, we attempted to clarify the mechanism of enhanced fibrinolytic activity related to open heart surgery. Immediately after the operation, the t-PA concentration increased gradually, and this increase in t-PA concentration continued until 24 hours after the operation. On the other hand, the FDP concentration began to increase at 2 days after the operation, and thereafter the FDP concentration increase gradually. From the above results, it is concluded that the enhanced fibrinolytic activity was based on an increased concentration of t-PA in the circulating blood. Furthermore, the increase in t-PA may have been favorable for excluding excess thrombus such as hemostatic plugs.
論文
Databáze: OpenAIRE