Synthesis and Biological Evaluation of a New Series of Benzothiazole-Benzothiadiazine Conjugates as Antibacterial Agents

Autor: Kamal, A, Ahmed, SK, Reddy, KS, Khan, MNA, Shetty, RVCRNC, Siddhardha, B, Murty, USN, China, A, Nagaraja, V
Rok vydání: 2007
Předmět:
Zdroj: IndraStra Global.
ISSN: 2381-3652
Popis: A new series of benzothiazolo-benzothiadiazine hybrids (9a-g) has been synthesized and evaluated for their antibacterial activity against clinical isolates of Gram-positive and Gram-negative bacteria. Some of these hybrids in this series exhibited antibacterial activity comparable to ampicillin. In addition, some of the compounds showed DNA gyrase inhibitory activity at a moderate level compared to ciprofloxacin.
Databáze: OpenAIRE