STEREOSELECTIVE TOTAL SYNTHESIS OF (2R,2'S,3Z)-1-0-(2-METHOXYHEXADECENYL)GLYCEROL AND (2R,2'S)-1-(2'-METHOXYHEXADECYL)GLYCEROL-POTENTIAL ANTITUMOR COMPOUNDS FROM SHARK LIVER OIL
| Autor: | BAIG, MHA, BASKARAN, S, BANERJEE, S, TRIVEDI, GK |
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| Jazyk: | angličtina |
| Rok vydání: | 1995 |
| Zdroj: | IndraStra Global. |
| ISSN: | 2381-3652 |
| Popis: | A simple and high yielding route for the stereoselective synthesis of alkyl glycerol ethers namely (2R,2'S,3Z)-1-O-(2-methoxyhexadecenyl)glycerol 1 and (2R,2'S)-1-(2'-methoxyhexadecyl) glycerol 2, isolated form Shark liver oil is reported. The key reaction involves the Wittig olefination of the chiral aldehyde 12 with the ylide generated from tridecyl triphenyl phosphonium bromide results in the formation of compound 13, a precursor for the title compounds 1 and 2. |
| Databáze: | OpenAIRE |
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