Interaction of Co, Mn, Mg and AI with d(GCGTACGC): a spectroscopic study

Autor: Rajan, MT, Champion, D, Kumar, CS, Vishnuvardhan, D, Jagannatha Rao, KS, Viswamitra, MA
Jazyk: angličtina
Rok vydání: 1996
Předmět:
Zdroj: IndraStra Global.
ISSN: 2381-3652
Popis: Spectroscopic study on the interactions of trace elements Co, Mn, Mg and Al with d(GCGTACGC) indicated the following: Al and Mg did not alter T-m values. Mn enhanced T-m at lower concentration and decreased it at higher concentrations. Interestingly Co at higher concentration elevated the T-m. These studies also showed lower concentrations of Mn displaced EtBr, whereas Al could displace it at higher ionic strength. Mg and Co displaced EtBr fluorescence at moderate concentrations. The binding constant values and CD spectra clearly indicated strong binding of these elements to DNA.
Databáze: OpenAIRE