| Autor: |
Bashier, Alaaeldin M., Fadlallah, Ayman Aly Seddik, Alhashemi, Nada, Thadani, Puja Murli, Abdelgadir, Elamin, Rashid, Fauzia |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
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| Zdroj: |
Advances in Endocrinology. |
| ISSN: |
2356-668X |
| DOI: |
10.1155/2015/254042 |
| Popis: |
Diabetes mellitus is the commonest cause of CKD. It is the leading cause of new patients requiring renal replacement therapy, accounting for 40%, 34%, and 30% of cases in United States, Germany, and Australia, respectively. Recent studies have shown that a low-molecular weight protein, cystatin C, freely filtered by the kidneys is a novel biomarker that may be used for detection of early renal dysfunction in patients with type 1 or type 2 diabetes. Cystatin C has also been shown to detect cardiovascular disease in patients with diabetes and it may also be linked with incident type 2 diabetes in obese patients. We aim to review current evidence based literature on use of cystatin C for early detection of diabetic nephropathy due to type 1 and type 2 diabetes in comparison to conventional methods and explore its association with other comorbidities. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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