Effectiveness and Safety of Compound Chinese Medicine plus Routine Western Medicine in In-Stent Restenosis: A Meta-Analysis and Systematic Review

Autor: Liu, Lu, Liu, Jing, Gao, Qun, Wu, Yang, Lu, Jinjin, Wan, Jie, Li, Yan, Cui, Xiaoyun, Zhou, Kun, Jia, Wenhao, Huang, Yanchao, Qu, Wenbai, Lin, Qian
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Evidence-Based Complementary and Alternative Medicine.
ISSN: 1741-427X
DOI: 10.1155/2018/6207524
Popis: Objective. To examine the effects and safety of oral compound Chinese medicine (CCM) plus routine western medicine (RWM) in in-stent restenosis (ISR). Methods. Various electronic databases (CBM, CNKI, VIP, Wanfang, PubMed, EMBASE, and Cochrane Library) were searched until April 2017. The quality of the included studies was evaluated, and meta-analyses were performed using RevMan5.3 and STATA 12.0 software. Moreover, funnel plot and Egger’s publication bias plots were analysed to identify publication bias and adverse reactions were reported. A sensitive analysis was carried out according to the quality score. Results. In all, 40 RCTs involving 4536 patients were selected for this review. The pooled estimates of three studies showed that the benefit to the number of ISRs (NoR) was more substantial for CCM plus RWM than for RWM alone (RR 0.24, 95% CI 0.10 to 0.57, P=0.001;I2=0%, P=0.81). The rate of ISR was significantly lower for CCM plus RWM than for the same RWM alone (RR 0.44, 95% CI 0.37 to 0.53, P
Databáze: OpenAIRE