Systemic Lupus Erythematosus with Multiple Autoimmune Disease Presented with Extensive Peripheral Gangrene

Autor:	Alzughayyar, Tareq Z., Zalloum, Jihad Samer, Elqadi, Mohammad N., Abukhalaf, Sadi A., Abunejma, Fawzy M., Alkhanafsa, Mohammed M. Y., Haif, Motasem H. M., Alqarajeh, Firas, Mesk, Mo’min R., Misk, Rami A.
Jazyk:	angličtina
Rok vydání:	2020
Předmět:	Article Subject immune system diseases skin and connective tissue diseases
Zdroj:	Case Reports in Rheumatology.
ISSN:	2090-6889
DOI:	10.1155/2020/8278275
Popis:	Systemic lupus erythematosus (SLE) is an autoimmune disease and can be associated with other autoimmune diseases. SLE usually presents with skin change and rarely presents with gangrene. SLE gangrene usually involves the digits of upper extremities. We report the first case of SLE associated with an extremely rare constellation of neuromyelitis Optica (NMO) and diabetes mellitus type 1, presented with a rare form of the SLE gangrene which involves bilateral lower extremities up to midlegs, a case that has not yet been reported in the literature. Although SLE gangrene may respond to immunosuppressants, it has a high risk of complications that can end up with amputations.
Databáze:	OpenAIRE
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