| Autor: |
Vasconcelos, Joana, Domingos, João, Bastos, Lia, Baptista, Teresa, Mansinho, Kamal |
| Jazyk: |
angličtina |
| Rok vydání: |
2022 |
| Předmět: |
|
| Zdroj: |
Case Reports in Infectious Diseases. |
| ISSN: |
2090-6625 |
| DOI: |
10.1155/2022/3890309 |
| Popis: |
Chronic hepatitis B (CHB) is a potentially life-threatening and prevalent disease worldwide. Far from attaining the ultimate treatment goal, hepatitis B virus (HBV) infection eradication, the two current therapeutic options aim to prevent progression to end-stage liver disease, maintaining long-term suppression of HBV replication. Pegylated interferon-α (PEG-INFα) is often poorly tolerated and disregarded considering the orally administered nucleos(t)ide analogues. However, PEG-INFα may achieve similar treatment endpoints with a finite course of treatment. We report a case of PEG-INFα-treated CHB that attained sustained off-treatment virological response with only 16 weeks of treatment, with loss of both HBeAg and HBsAg (this latter the optimal treatment endpoint). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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