Isolated Central Nervous System Vasculitis Associated with Antiribonuclear Protein Antibody

Autor: Awad, Amer M., Stevenson, Mathew
Jazyk: angličtina
Rok vydání: 2011
Předmět:
Zdroj: Case Reports in Neurological Medicine.
ISSN: 2090-6668
DOI: 10.1155/2011/495201
Popis: We describe the case of a young woman who was referred to a tertiary care center with unexplained subacute progressive encephalopathy preceded by long-standing severe headaches. Her extensive workup was remarkable for abnormal intracranial angiography suggestive of small- and medium-vessel vasculitis, persistently elevated protein in the cerebrospinal fluid and persistently high titers of antiribonuclear protein antibody. The patient showed a modest response to intravenous high-dose steroids. We propose that the patient's neurologic disease is secondary to immune-mediated central nervous system vasculitis, possibly as an initial manifestation of mixed connective tissue disease.
Databáze: OpenAIRE