Hypertension: The Neglected Complication of Transplantation

Autor: Aparicio, Lucas S., Alfie, José, Barochiner, Jessica, Cuffaro, Paula E., Rada, Marcelo, Morales, Margarita, Galarza, Carlos, Waisman, Gabriel D.
Jazyk: angličtina
Rok vydání: 2013
Předmět:
Zdroj: ISRN Hypertension.
DOI: 10.5402/2013/165937
Popis: Arterial hypertension and transplantation are closely linked, and its association may promote impaired graft and overall survival. Since the introduction of calcineurin inhibitors, it is observed in 50–80% of transplanted patients. However, many pathophysiological mechanisms are involved in its genesis. In this review, we intend to provide an updated overview of these mechanisms, dealing with the causes common to all kinds of transplantation and emphasizing special cases with distinct features, and to give a perspective on the pharmacological approach, in order to help clinicians in the management of this frequent complication.
Databáze: OpenAIRE