The Protective Effect of Traditional Chinese Medicine on Liver Ischemia-Reperfusion Injury

Autor: Ma, Wen, Tang, Songling, Xie, Dina, Gu, Guoqiang, Gan, Lu
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Evidence-Based Complementary and Alternative Medicine.
ISSN: 1741-427X
DOI: 10.1155/2021/5564401
Popis: Liver ischemia-reperfusion (I/R) injury occurs during transplantation and major hepatic surgery, which may lead to postoperative liver dysfunction. More and more traditional Chinese medicines (TCMs) have been used to treat liver ischemia-reperfusion injury. The purpose of this review is to evaluate the different protective effects of TCMs in the treatment of liver ischemia-reperfusion injury and to summarize its possible mechanisms. The results indicate that TCMs attenuate liver I/R injury via multiple mechanisms, including antioxidation stress, anti-inflammatory response, antiapoptosis, and inhibiting endoplasmic reticulum stress. However, the in-depth mechanism of the protective effects of these traditional Chinese medicines still remains unknown.
Databáze: OpenAIRE