| Autor: |
Sansone, Andrea, Cignarelli, Angelo, Sansone, Massimiliano, Romanelli, Francesco, Corona, Giovanni, Gianfrilli, Daniele, Isidori, Andrea, Giorgino, Francesco, Lenzi, Andrea |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
International Journal of Endocrinology. |
| ISSN: |
1687-8337 |
| DOI: |
10.1155/2018/7424792 |
| Popis: |
Objectives. Elevated levels of serum homocysteine (Hcy) have been associated with cardiovascular diseases and endothelial dysfunction, conditions closely associated with erectile dysfunction (ED). This meta-analysis was aimed to assess serum Hcy levels in subjects with ED compared to controls in order to clarify the role of Hcy in the pathogenesis of ED. Methods. Medline, Embase, and the Cochrane Library were searched for publications investigating the possible association between ED and Hcy. Results were restricted by language, but no time restriction was applied. Standardized mean difference (SMD) was obtained by random effect models. Results. A total of 9 studies were included in the analysis with a total of 1320 subjects (489 subjects with ED; 831 subjects without ED). Pooled estimate was in favor of increased Hcy in subjects with ED with a SMD of 1.00, 95% CI 0.65–1.35, p |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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