A Child as a Donor for Hematopoietic Stem Cell Transplantation: Bioethical Justification—A Case Study on Sickle Cell Disease

Autor: Pereira, Andrea Z., Hellman, Ricardo, Hamerschlak, Nelson, Kondo, Andrea, Souza, Polianna Mara Rodrigues de, Pedreira, Wilson LeiteJr., Mantovani, Luiz Fernando Alves Lima, Troster, Eduardo Juan, Grunspun, Henrique, Bueno, Marco Aurélio Scarpinella
Jazyk: angličtina
Rok vydání: 2017
Předmět:
Zdroj: Case Reports in Hematology.
ISSN: 2090-6560
DOI: 10.1155/2017/8394732
Popis: Hematopoietic stem cell transplantation (HSCT) is an important treatment option for children with severe and refractory sickle cell disease (SCD) with debilitating clinical complications. HSCT with cells from the bone marrow of a HLA-identical sibling used in SCD has a low mortality risk, high cure rate, and high event-free survival rate after a median follow-up of 5-6 years. However, matched donors are found in only about 20% of the patients. A boy aged 8 years with SCD had a sister
Databáze: OpenAIRE