Lymphocyte Subpopulations in Pulmonary Tuberculosis Patients

Autor: Deveci, Figen, Akbulut, H. Handan, Celik, Ilhami, Muz, M. Hamdi, İlhan, Fulya
Jazyk: angličtina
Rok vydání: 2006
Předmět:
Zdroj: Mediators of Inflammation.
ISSN: 0962-9351
DOI: 10.1155/MI/2006/89070
Popis: Protection against Mycobacterium tuberculosis is based on cell-mediated immunity, most importantly involving CD4+ and CD8+ T-cell subsets. The aim of this study was to evaluate CD4+ and CD8+ T-cell profiles and CD19+ and CD3-CD(16+56)+ populations in patients with pulmonary tuberculosis. CD4+ and CD8+ T cells, B-lymphocytes, and natural killer (NK) cells were evaluated in 75 active (APTB) and 25 inactive (IPTB) pulmonary tuberculosis cases and 20 healthy subjects (HCs). The results were compared at different stages of antituberculosis treatment in the APTB patients and also according to X-ray findings in the newly diagnosed APTB patients. The percentages of CD4+ T cells were significantly lower (P
Databáze: OpenAIRE