Systemic Mastocytosis in a Patient with BCR-ABL1-Positive Chronic Myeloid Leukemia in the Remission Phase

Autor: Fokoloros, Christos, Foukas, Periklis, Georgakopoulos, Nikolaos, Tsakiraki, Zoi, Bouchla, Anthi, Pappa, Vasilliki, Katoulis, Alexandros, Makris, Michael, Papageorgiou, Sotirios
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Case Reports in Hematology.
ISSN: 2090-6560
DOI: 10.1155/2022/7251658
Popis: Systemic mastocytosis (SM) comprises a group of rare disorders resulting from tissue infiltration by pathological mast cells. In a percentage ranging from 5 to 40% in various patient series, SM appears to be associated with an accompanying hematologic neoplasm (SM-AHN). The coexistence of SM with chronic myelogenous leukemia (CML) is extremely rare with only 3 cases in the literature. The natural course of CML has changed dramatically over the past 2 decades with the use of tyrosine kinase inhibitors (TKIs). We report a case of diagnosing SM in a patient in complete molecular remission of CML after stopping TKI treatment.
Databáze: OpenAIRE
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